Chorionic Villus Sampling / Amniocentesis

Nakshatra Clinic

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Chorionic Villus Sampling / Amniocentesis

Overview

A CVS test, or chorionic villus sampling, collects placental tissue and tests it for chromosomal abnormalities and genetic diseases including Down syndrome. The placenta is a uterine organ that delivers nutrients and blood to the infant. It is to blame.

They are tiny finger-like extensions of placental tissue that transport the fetus’ genetic material. The availability of lab testing at the time of surgery may allow you to be checked for further genetic illnesses and anomalies.

About Chorionic Villus Sampling / Amniocentesis

Chorionic Villus Sampling / Amniocentesis

Samples of your baby’s chorionic villus may provide information about the genetic make-up of your child. Pregnancy management or your willingness to continue your pregnancy may be jeopardized if you choose not to undergo a chorionic villus sample.
Chorionic villus sampling, like other prenatal diagnostic procedures like amniocentesis, is often performed between weeks 11 and 14 of pregnancy.
If any of the following apply, you should think about chorionic villus sampling:

  • You had a positive prenatal screening test. A screening test’s results may indicate the need for additional testing, such as a chorionic villus sample, to determine the presence or absence of a condition.
  • There was a chromosomal problem in a prior pregnancy that you need to know about. Previous pregnancies with Down syndrome or other chromosomal disorders may put the current pregnancy at risk as well.
  • There is a chance that you are above the age of 35. When a woman is 35 or older, her baby is more likely to be born with a chromosomal abnormality like Down syndrome.
  • Your family has a genetic condition, or you or your spouse are a known carrier. While chorionic villus sampling is most often used to diagnose Down syndrome, it may also detect other genetic illnesses such as Tay-Sachs and cystic fibrosis.

Certain birth abnormalities, such as neural tube defects, cannot be detected via chorionic villus sampling. An ultrasound or genetic amniocentesis may be suggested instead of neural tube abnormalities are a concern.
You may be advised to avoid transcervical chorionic villus sampling, which is performed through the vaginal canal if you have the following conditions:

  • Herpes is an example of an active cervical or vaginal infection
  • Two-week history of vaginal bleeding or spotting
  • Having a uterus tilted or having noncancerous growths in your cervix or the bottom portion of your uterus blocks access to your placenta

Transabdominal chorionic villus sampling, which involves taking a sample from the uterus via the abdominal wall, should only be performed if:

  • When you’re pregnant, the placenta attaches to the rear of the uterus.

In the first trimester of pregnancy, a chorionic villus sample may be utilized for genetic and chromosomal testing. Here are a few reasons why a woman might choose to have CVS:

  • There is a history of genetic illness, chromosomal abnormalities, or metabolic disorders in the patient’s immediate family.
  • Mothers above the age of 35 at the time of delivery
  • Chances of contracting a hereditary illness that is exclusive to women
  • Ultrasounds performed in the past with potentially problematic or abnormal results
  • Unusual results from a test using cell-free DNA

Your doctor may suggest a chorionic villus sample for various reasons.

There are many hazards associated with chorionic villus sampling, including the following:

  • Miscarriage: Chorionic villus sampling has a 0.22 percent chance of miscarriage.Rh sensitization: During chorionic villus sampling, some infant blood cells may reach your bloodstream. If you have Rh-negative blood and haven’t developed antibodies against Rh-positive blood, you’ll be injected with Rh immune globulin following your chorionic villus sample.
  • Stop producing Rh antibodies, which may damage the baby’s red blood cells if they cross the placenta after birth. A blood test may show whether your body has begun generating antibodies.
  • Infection: A uterine infection may occur very infrequently as a result of chorionic villus sampling.

Chorionic villus sampling has been linked in the past to finger and toe malformations in babies. However, only if the operation is performed before week 10 of pregnancy does the danger seem to be significant.

Your doctor or genetic counselor can explain your chorionic villus sample findings. When test findings are ambiguous, amniocentesis, another prenatal diagnostic procedure, is required.
A false-positive test occurs when a chorionic villus sample is positive although no illness is present. The chorionic villus sample cannot detect all birth abnormalities, including spina bifida and others.
Your kid may have a chromosomal or genetic issue that can’t be addressed if you take chorionic villus samples. During this tough time, seek help from your medical staff and loved ones.